保護眼睛免受藥物副作用:了解藥物對乾眼症的影響

十一月 27, 2019

許多藥物可能導致乾眼症症狀, 包括抗粉刺藥物與抗組織胺藥物。 來看看最常見的幾種吧1-5:

避孕藥

雌激素可能會影響淚膜中的水分生成, 進而使雙眼乾澀。 若您有乾眼症, 使用避孕藥或進行針對更年期的荷爾蒙替代療法, 請諮詢您的婦科醫師。1-5

藥物引起的乾眼症:瞭解自己的藥物
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

抗高血壓藥物

被歸類為 Beta 受體阻斷劑的抗高血壓藥物可能會減少淚液生成,並導致乾眼症症狀1-5

藥物引起的乾眼症:瞭解自己的藥物
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

抗組織胺藥物

這種藥物能阻絕身體對於過敏引發物的反應,避免淚液過度分泌或流鼻水等,但也會在一定程度上抑制淚腺,導致沒有足夠的淚液可以潤滑雙眼。1-5

藥物引起的乾眼症:瞭解自己的藥物
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

鼻部去充血劑

天冷或過敏時,您可以使用充血劑來緩解鼻塞,因為它能減緩鼻腔血管的腫脹,讓呼吸恢復暢通。但很不幸地,它也可能減少淚液量。1-5

Drug-induced dry eye: Nasal decongestants
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

抗憂鬱藥物

抗焦慮藥物與三環抗憂鬱藥物能阻絕腺體活化的訊號傳遞。這也可能影響淚腺,導致雙眼分泌較少淚液。1-5

藥物引起的乾眼症:瞭解自己的藥物
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

止痛藥物

若您服用布洛芬 (ibuprofen) 與乙醯胺酚 (paracetamol) 等 OTC止痛藥疼痛藥物,特別是大量服用的話,您可能會出現乾眼症症狀。1-5

藥物引起的乾眼症:瞭解自己的藥物
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

抗粉刺藥物

若您有嚴重粉刺問題,您的醫生可能會開口服A 酸給您,這是一種維他命 A 的衍生物,能減少肌膚的油脂分泌。它的副作用是影響淚膜的脂質層生產,引起淚膜的不穩定與水分蒸發的增加,進而導致乾眼症。1-5

藥物引起的乾眼症:瞭解自己的藥物
參考資料
  1. Fraunfelder, Frederick T, et al. The role of medications in causing dry eye. Journal of ophthalmology vol. 2012 (2012): 285851. doi:10.1155/2012/285851
  2. J. Daniel Nelson, et al. Non-hormonal Systemic Medications and Dry Eye. Ocul Surf. 2011 Oct;9(4):212-26. https://doi.org/10.1016/S1542-0124(11)70034-9
  3. Jaanus SD. Ocular side effects of selected systemic drugs. Optom Clin. 1992;2(4):73-96. https://www.ncbi.nlm.nih.gov/pubmed/1363080
  4. Junping Li, Ramesh C. Tripathi, Brenda J. Tripathi. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. https://www.ncbi.nlm.nih.gov/pubmed/18217789
  5. Facts About Dry Eye. The national eye institute. https://nei.nih.gov/health/dryeye/dryeye. Last accessed August 25, 2019.

若您覺得自己的藥物可能導致乾眼症,請先與醫師討論是否有其他方案,請勿自行停藥。在大部分的狀況中,藥物引發的乾眼症會在停藥後消失,但這可能會需要數週甚至是數月的時間。

檢測乾眼症
 
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此快速試驗不能做為醫學評估,也不能取代眼科專業人員的醫療、診斷或處方。

관련 게시물

檢測乾眼症
 
讓我們使用DEQ-5 評估工具
快速評估您的症狀
 現在開始
 
此快速試驗不能做為醫學評估,也不能取代眼科專業人員的醫療、診斷或處方。
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眼睛知識家
睜眼比賽
眼睛知識家 的睜眼比賽過程中,請別眨眼。若您在十秒內眨了眼,那麼您可能有乾眼症。
 現在開始   ▶

這項快速的測試並非醫療評估,且並不能取代眼科醫師的看診,他們能做出與治療、診斷或開立藥物相關的決定。